So I just thought of this.

If HRG got a transfusion of Claire's blood...that means he has some of her invinci-cells in him. So, does that mean he has regeneration now? I mean the cells can replicate themselves, and regenerate so its not like they are going away or anything.

So...is he like semi-indestructible now?

As was discussed in various other threads concerning a character receiving a healing-factor blood transfusion, I think away from the superpowered brain, the power held in the cells won't be permanent...

Correct, the cells will heal all that they can until used up. (ie he might not need glasses now lol) Then his body will continue to make normal cells and he will return to normal healing state.